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Anatomy Notes > Blog > Difference Between > 44 Difference between Small Intestine and Large Intestine
Difference Between

44 Difference between Small Intestine and Large Intestine

TEAM ANATOMY NOTES
Last updated: June 3, 2024 1:55 am
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The human digestive system relies on the small and large intestines to break down food and absorb nutrients. Though named differently, their distinctions go beyond size. To efficiently extract nutrients and eliminate trash, these distinctions are crucial.

The small intestine is longer and thinner than the large intestine and has three segments: duodenum, jejunum, and ileum. This complex organ absorbs most nutrients. Microvilli cover tiny finger-like villi on the small intestine walls. The intestine’s surface area increases, making it easier to absorb nutrients including carbs, proteins, lipids, and vitamins. The liver and pancreas provide bile and digestive enzymes to the small intestine, which breaks down food.

The colon is shorter and broader than the big intestine. The main role is to absorb water and electrolytes from undigested food to generate feces for disposal. The big intestine has a smoother lining and no villi. Beneficial gut microbiota microorganisms distinguish the large intestine. These bacteria produce gases and vitamin K and B vitamins by fermenting undigested carbohydrates.

Material movement via each organ differs. Peristalsis moves food and digestive fluids through the small intestine, ensuring effective mixing and nutritional absorption. However, the large intestine moves slowly and deliberately to compress feces and reabsorb water.

While both the small and large intestines are essential to digestion and health, they serve different functions. Due to its enormous surface area and villi-covered lining, the small intestine absorbs nutrients well, whereas the large intestine’s bacteria absorb water and generate feces. These distinctions help us understand these organs’ complicated relationship and how they affect digestion.

Also Read: An Overview of the Lymphatic System’s Function & Organs

Here are 44 differences between the small intestine and the large intestine:

S.No.

Aspects

Small Intestine

Large Intestine

1

Location

Located between the stomach and the large intestine

Located after the small intestine and before the rectum

2

Length

Longer in length (about 20 feet or 6 meters)

Shorter in length (about 5 feet or 1.5 meters)

3

Diameter

Smaller in diameter than the large intestine

Larger in diameter than the small intestine

4

Subdivisions

Divided into three parts: duodenum, jejunum, and ileum

Divided into cecum, colon, and rectum

5

Digestive Function

Main site of nutrient absorption, including carbohydrates, proteins, and fats

Absorbs water and electrolytes, and stores waste

6

Villi and Microvilli

Contains villi and microvilli to increase surface area for absorption

Lacks villi and microvilli

7

Mucosal Surface Area

Has a larger mucosal surface area for absorption

Has a smaller mucosal surface area

8

Muscular Layer

Has a thicker muscular layer for mixing and propelling contents

Has a thinner muscular layer

9

Absorption Sites

Absorbs nutrients, vitamins, and minerals, including iron and calcium

Absorbs water, electrolytes, and some vitamins

10

Transit Time

Faster transit time (around 4-6 hours)

Slower transit time (around 12-48 hours)

11

Bile and Pancreatic Enzymes

Receives bile and pancreatic enzymes for digestion

Receives minimal bile and enzymes

12

Feces Formation

Feces are not present, as it’s primarily an absorption site

Feces formation begins in the cecum

13

Fecal Composition

Feces contain water, electrolytes, and undigested food residues

Feces primarily consist of indigestible materials

14

Role in Water Absorption

Limited role in water absorption

Main site for water absorption

15

Gut Flora

Contains relatively fewer gut bacteria

Contains a large population of gut bacteria

16

Role in Vitamin Synthesis

Does not synthesize significant vitamins

Synthesizes certain vitamins (e.g., vitamin K, some B vitamins)

17

Role in Immune System

Contains isolated lymphoid nodules (Peyer’s patches)

Contains more significant lymphoid tissue

18

Storage of Fecal Material

Does not store fecal material

Stores fecal material before elimination

19

Absorption of Bile Salts

Absorbs and recycles bile salts

Does not absorb bile salts

20

Stomach Connection

Connected directly to the stomach via the pyloric sphincter

Connected to the stomach via the ileocecal valve

21

Role in Gas Production

Limited role in gas production

Significant gas production by gut bacteria

22

Hormone Secretion

Secretes hormones like secretin and cholecystokinin

Secretes hormones like gastrin and motilin

23

Role in Formation of Fecal Mass

Does not contribute to the formation of fecal mass

Begins the process of forming fecal mass

24

Main Function

Primary function is absorption and digestion of nutrients

Primary function is absorption of water and electrolytes

25

Blood Supply

Receives blood supply from the superior mesenteric artery

Receives blood supply from the superior mesenteric artery and inferior mesenteric artery

26

Storage of Fecal Material

Does not store fecal material

Stores fecal material before elimination

27

Goblet Cells

Contains goblet cells that produce mucus for lubrication

Contains goblet cells, which produce mucus for protection and lubrication

28

Main Absorption Site for Nutrients

Primary site for absorption of nutrients and minerals

Absorbs water and some nutrients

29

Role in Stool Formation

Does not contribute to stool formation

Begins the process of stool formation

30

Role in Stool Consistency

Does not significantly influence stool consistency

Can influence stool consistency

31

Role in Absorption of Electrolytes

Limited role in electrolyte absorption

Main site for electrolyte absorption

32

Main Digestive Enzymes

Receives digestive enzymes from the pancreas and liver

Does not receive digestive enzymes

33

Gastrointestinal Diseases

Less susceptible to gastrointestinal diseases

Can be prone to conditions like diverticulitis, colitis, and irritable bowel syndrome

34

Motility

Exhibits faster peristaltic contractions

Exhibits slower peristaltic contractions

35

Secretion of Mucus

Produces mucus primarily for lubrication

Produces mucus for protection and lubrication

36

Role in Digestive Enzyme Production

Does not produce digestive enzymes

Does not produce digestive enzymes

37

Role in Stool Formation

Does not significantly contribute to stool formation

Begins the process of stool formation

38

Role in Absorption of Electrolytes

Limited role in electrolyte absorption

Main site for electrolyte absorption

39

Main Digestive Enzymes

Receives digestive enzymes from the pancreas and liver

Does not receive digestive enzymes

40

Gastrointestinal Diseases

Less susceptible to gastrointestinal diseases

Can be prone to conditions like diverticulitis, colitis, and irritable bowel syndrome

41

Motility

Exhibits faster peristaltic contractions

Exhibits slower peristaltic contractions

42

Secretion of Mucus

Produces mucus primarily for lubrication

Produces mucus for protection and lubrication

43

Role in Digestive Enzyme Production

Does not produce digestive enzymes

Does not produce digestive enzymes

44

Role in Hormone Production

Secretes hormones related to digestion (e.g., secretin)

Secretes hormones related to digestion and motility (e.g., gastrin)

 Also Read: Gastrointestinal System – Intro, Functions, Movements & Organs Associated

Frequently Asked Questions (FAQS)

  1. What are the small and big intestines’ principal functions?

The small intestine absorbs most nutrients from digested food. Villi and microvilli improve the surface area for effective absorption of carbs, proteins, lipids, and vitamins. In contrast, the large intestine absorbs water and electrolytes and forms and compacts feces. It contains intestinal bacteria that ferment and create vitamins.

 

  1. How do the structures of the small intestine and large intestine differ?

The small intestine’s villi and microvilli maximize nutrition absorption surface area. Large intestines have smoother inner linings and lack these features. The small intestine’s considerable folding and three segments (duodenum, jejunum, and ileum) help it absorb nutrients, whereas the large intestine’s broad width helps it absorb water.

 

  1. What do enzymes and bacteria perform in these organs?

The pancreas supplies digesting enzymes and the liver bile to the small intestine. These enzymes convert food into absorbable molecules. The microbiota of the large intestine is varied. These bacteria ferment undigested carbs, generating gases and vitamins K and B.

 

  1. Do the small and big intestines transport material differently?

Peristalsis moves food and digestive fluids through the small intestine. This movement mixes and absorbs nutrients efficiently. In contrast, the large intestine moves slowly and deliberately to compress feces and absorb water. This slow movement is essential for well-structured feces.

 

  1. Do the small and big intestines act separately?

No, these organs work together to digest and use nutrients. The small intestine breaks down stomach-digested food for nutrients. The bloodstream transports ingested nutrients throughout the body. The large intestine reclaims water and microorganisms finish the feces with the undigested material. Both organs work together to support the body’s nutritional demands and waste disposal.

 

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