Embryology is the study of the origin and the development of embryo till maturation.
In this branch of human anatomy we investigate the molecular, cellular, and structural factors which contribute to the formation of an organism, it is also called as developmental anatomy.
The study of embryo development helps us to gain knowledge for creating health care strategies for better reproductive outcomes.
Prenatal development includes repeated division of cells in the body which results in growth in size, complexity, the structural and functional differentiation of body.
SUBDIVISIONS OF EMBRYOLOGY
- It is the study of development during pre-embryonic and embryonic periods (first 8 weeks after fertilization).
- During this period, the single-celled zygote is converted by cell multiplication, migration and reorganization into a miniature form of an individual with various organs and organ systems of the body.
- It is a detailed study of the formation of primordia and their structural and early functional organization into various organs and systems of the body.
- It is further subdivided into the development of cardiovascular the system, digestive system, urinary system, genital system, etc.
- It is the study of embryos in different species of animals.
- It is for understanding the effects of certain drugs, environmental changes that are induced (exposure to radiation, stress) on the growth and development of embryos and foetuses of lower animals.’
- The knowledge gained from these experiments can be used for avoiding the harmful effects of human development.
- It is a vigorous and promising branch of embryology.
- This is a branch of embryology that deals with abnormal embryonic and foetal development, i.e. congenital abnormalities or birth defects.
IMPORTANCE OF EMBRYOLOGY IN THE MEDICAL PROFESSION:-
- This subject tells us how a single cell (the fertilized ovum, i.e. zygote) develops into a new-born, containing numerous tissues and organs.
- Normal adult anatomy: This knowledge helps us to understand many complicated facts of adult anatomy like the location and relations of organs to one another.
- Examples—on the location of the heart on the left side of the thoracic cavity, liver on the right side of the abdominal cavity and its closeness to the stomach.
- Embryology helps us understand why some children are born with organs that are abnormal.
- Appreciation of the factors responsible for abnormal development assists us in preventing or treating such abnormalities.
- Examples—exposure to radiation during pregnancy, use of certain medications during pregnancy or a genetic abnormality that exists in the family.
Understanding postnatal and adulthood diseases
- The mechanisms (molecular and cellular) taking place during the development of embryo play a key role in the development of a wide range of diseases in adult life.
- Examples—that can vary from the absence of an ear or presence of an extra finger to hypertension, diabetes, depression, cardiovascular and renal diseases.
- This is known as foetal programming of adult diseases.
Health care strategies for the better reproductive outcome
- Knowledge of embryology facilitates interpretation of the results of various techniques like foetal ultrasound, amniocentesis, and chorionic villous biopsy.
- Based on the results, appropriate treatment can be planned.
- Example—performing surgeries for correction of a defect in the diaphragm prenatally; postnatal correction of a cardiac defect; a medical line of management of a diabetic or hypertensive mother.
Therapeutic procedures for infertility/fertility-related problems
- If the woman is unable to conceive by natural methods, alternate methods like cloning and in vitro fertilization can be planned.
- For spacing the pregnancies, various birth control methods (medical and surgical) are available.
- Basic knowledge of embryology is required for understanding the mechanism of action of these methods.
Stem cell therapy
- Cells forming tissues in the embryo are called stem cells. These are undifferentiated cells that can differentiate into specialized cell types.
- It is an uncommitted cell and depending on the signal it receives, it can develop into many specialized cells.
- These cells are capable of treating certain diseases in postnatal life.
Basic Process in Embryology
- Mitotic division
- Meiotic division
- Number of cells
- Size of cells
- Intercellular substance